Whitney Able's acting career started with a role in the low-budget film Age of Kali in 2005. In 2006, Whitney then portrayed Eve in the film Dead Lenny which was released direct-to-DVD. Whitney obtained a role in the pilot episode of the TV show Secrets of a Small Town, however the show was not picked up by the American Broadcasting Company (ABC). ABC did pick her up for a guest role in the show Rodney. Able's breakout role was in the 2006 horror film All the Boys Love Mandy Lane, portraying the bitchy but also sympathetic cheerleader Chloe. The film co-starred Amber Heard. She has since had roles in many films and has appeared in guest roles in television series including CSI: New York, and Cold Case. In 2007, Whitney next film role came in Emmanuelle Vaugier's horror vehicle Unearthed, in which Able plays Ally. The film was one of the 8 Films to Die For at Horrorfest. She also starred in the film Love and Mary and Remarkable Power alongside Tom Arnold and Kevin Nealon. After appearing in a number of roles in independent films, in 2010, she was suggested for the lead role of Samantha to Gareth Edwards, Director of the upcoming Rogue One: A Star Wars Story, for the film Monsters. She won the lead role alongside co-star Scott McNairy. The film was critically praised. She married her co-star Scott McNairy in 2010 and has appeared in other films since, such as Straight A's (2013) with Luke Wilson and Anna Paquin and A Walk Among the Tombstones (2014) with Liam Neeson. Most recently she starred in the Joe Dante produced thriller DARK (2015). She received an Outstanding Performance by a Leading Actress Nomination for her role in DARK at the Oldenburg International Film Festival in Germany. She ranked #83 on the Maxim magazine Hot 100 of 2008 list.